Pipeline
16 Pipelines Reached PCC in Six Months40+ More Advancing
Automated Wet-Lab PlatformHigh-Throughput Protein Production and Profiling
2,000 proteins per run | 8-day end-to-end workflow From gene synthesis to full property readout
Expression & Purification
5 DaysExpression and purificationProperty Profiling
2 DaysMulti-parameter characterizationProperties profiledBLI affinity • specificity • expressibility • stability • humanization level • purity • immunogenicity
Affinity Screening,Blocking and Functional Activity Testing
Y axis is log KD; higher = stronger. The ★ and dotted line of the same colour are the same number (wt measured value / that value extended as a reference), so the line passes through the star. Open circle + arrow = kdis at the BLI limit (<1e-7); that KD is an upper bound only.
Three Humanized Antibodies Delivered IC50 Values Slightly Better than the Benchmark. These Four Antibodies Were Selected for Mid-Scale Expression and Preliminary Developability Assessment.
Case A: Humanized Antibody Purity Testing (SEC)
High Purity and Low Aggregation
Initial In Vivo Efficacy and Safety Assessment
In Vivo Results Show That the Candidate Molecules Delivered Good Efficacy and Were Close to the Benchmark. At the Same Time, No Obvious Toxic Side Effects Such as Weight Loss or Hair Loss Were Observed.
